Open Accessibility Menu

High Intensity Focused Ultrasound (HIFU) Treatment in Colorado

Minimally Invasive Treatment for Prostate Cancer

High Intensity Focused Ultrasound Prostate Ablation (HIFU) is a minimally invasive treatment option for localized prostate cancer that is performed on an outpatient basis. While your cancer may continue to be well-managed with active surveillance, some patients with early stage prostate cancer may benefit from treatment. HIFU therapy is specific to each patient’s cancer. This allows the physician to treat the areas of cancer exclusively – leaving the areas of the prostate not involved with cancer untouched. This means less risk of side effects such as urinary incontinence and erectile dysfunction, which are associated with more invasive treatments, such as radiation therapy or surgery.

Damian N. Sorce, MDColorado Urology's Dr. Damian Sorce utilizes this innovative treatment option to treat patients in the Denver Metro Area. He says, “HIFU is easily tailored to the individual patient and his disease, meaning if the cancer is localized to a small area of the prostate, we can perform a focal treatment – and if it is more widespread, we can do the entire gland. This flexibility is vastly different from radiation or surgery where it is all or nothing,” says Dr. Sorce. “As men are being diagnosed earlier and looking for less radical treatment options, HIFU offers a less invasive treatment option for those diagnosed with prostate cancer, and a choice that can put their lives back on track.”

About HIFU

High Intensity Focused Ultrasound (HIFU) uses ultrasound energy, or sound waves, to heat and destroy specifically targeted areas of cancerous tissue in the prostate. During HIFU, the sound waves pass through healthy tissue without causing damage. However, at the focal point of the sound waves the tissue temperature rises rapidly to 90 degrees Celsius, destroying the targeted tissue.

Magnifying Glass CartoonThe same principles are used when light is focused through a magnifying glass .

With HIFU, physicians have the ability to target and treat a small amount of tissue, which minimizes damage to areas around the prostate. This helps preserve normal urinary function and minimizes risk of erectile dysfunction.

How HIFU Works

HIFU is a minimally invasive option that utilizes Sonablate® technology. The advanced computer-controlled HIFU delivery device transports the ultrasound energy through a probe placed in the rectum. These waves are then targeted directly at the prostate for accurate ablation and destruction of the diseased tissue.

HIFU Planning Diagram

The HIFU technology consists of a console where the physician plans, monitors and adjusts HIFU treatment, a transrectal probe and a chiller, which is a safety device that keeps the rectum cool during treatment.

The HIFU device uses an ultrasound with multiple sensors which allows the physician to both accurately treat and safely monitor the progress of the treatment simultaneously. Due to its accuracy and precision, areas around the prostate are undamaged, which greatly reduces the risk of side effects such as erectile dysfunction and urinary incontinence.

In select cases, HIFU can be used for focal treatment, which is selective treatment of the cancerous areas within the prostate alone, leaving the non-cancerous portions undisturbed.

The radiation-free treatment is usually performed one time on an outpatient basis but can be repeated as necessary without causing adverse effects to surrounding tissues.

Benefits of HIFU

  • Low risk of side effects such as erectile dysfunction and incontinence often associated with radiation therapy or surgery
  • No damage to surrounding tissues or organs
  • HIFU can be repeated, if necessary, without damaging healthy tissue
  • One treatment with HIFU compared to multiple treatments sessions with radiation therapy/IMRT
  • Outpatient procedure is typically performed in one to four hours.
  • Radiation free
  • No blood loss
  • Quick recovery and return to normal activity within a few days
  • HIFU does not preclude other treatment options; men who choose HIFU and then require additional therapies still have other treatment options available
  • HIFU can be used as a prostate cancer salvage technique when other primary treatments such as radiation or cryotherapy fail

HIFU Outcomes

Percentages of Risk After HIFU

According to a recently published study, the oncological outcomes in patients with non-metastatic low- intermediate prostate cancer over 8 years were similar between focal therapy and radical prostatectomy1.

Candidates for HIFU Include:

HIFU is most effective for men who have early stage, localized prostate cancer that has not spread or metastasized outside the prostate.

HIFU may also be an effective therapy for recurrent prostate cancer when patients may not have any other treatment options.

For men who are potential candidates for this treatment, your urologist will discuss the benefits and risks of HIFU, and whether this treatment option is right for you.


1Shah, T.T., Reddy, D., Peters, M. et al. Focal therapy compared to radical prostatectomy for non-metastatic prostate cancer: a propensity score-matched study. Prostate Cancer Prostatic Dis 24, 567–574 (2021).